Publications Rossy

Publications Dr. Jérémie Rossy

Rossatti P, Redpath GMI, Ziegler L, Samson GPB, Clamagirand CD, Legler DF, Rossy J. 2022. Rapid increase in transferrin receptor recycling promotes adhesion during T cell activation. BMC Biol Aug 24;20(1):189. doi: 10.1186/s12915-022-01386-0.
Ecker M, Schregle R, Kapoor-Kaushik N, Rossatti P, Betzler VM, Kempe D, Biro M, Ariotti N, Redpath GMI, Rossy J. 2022. SNX9-induced membrane tubulation regulates CD28 cluster stability and signalling. Elife Jan 20;11:e67550. doi: 10.7554/eLife.67550.
Ecker M, Redpath GMI, Nicovich PR, Rossy J. 2021. Quantitative visualization of endocytic trafficking through photoactivation of fluorescent proteins. Mol Biol Cell Apr 19;32(9):892-902.
Redpath GMI, Betzler VM, Rossatti P, Rossy J. 2020. Membrane Heterogeneity Controls Cellular Endocytic Trafficking. Front Cell Dev Biol Aug 5;8:757. doi: 10.3389/fcell.2020.00757. eCollection 2020.
Schregle R, Mueller S, Legler DF, Rossy J, Krueger WA, Groettrup M. 2020. FAT10 localizes in dendritic cell aggresome-like induced structures and contributes to their disassembly. J Cell Sci Jun 16:jcs.240085. doi: 10.1242/jcs.240085. Online ahead of print.
Rossatti P, Ziegler L, Schregle R, Betzler VM, Ecker M, Rossy J. 2019. Cdc42 Couples T Cell Receptor Endocytosis to GRAF1-Mediated Tubular Invaginations of the Plasma Membrane. Cells Nov 4;8(11):1388. doi: 10.3390/cells8111388.
Redpath GMI, Ecker M, Kapoor-Kaushik N, Vartoukian H, Carnell M, Kempe D, Biro M, Ariotti N, Rossy J. 2019. Flotillins promote T cell receptor sorting through a fast Rab5-Rab11 endocytic recycling axis. Nat Commun Sep 26;10(1):4392. doi: 10.1038/s41467-019-12352-w.
Rossy J, Laufer JM, Legler DF. 2018. Role of Mechanotransduction and Tension in T Cell Function. Front. Immunol. 15 November 2018 | https://doi.org/10.3389/fimmu.2018.02638.
Compeer EB, Kraus F, Ecker M, Redpath G, Amiezer M, Rother N, Nicovich PR, Kapoor-Kaushik N, Deng Q, Samson GPB, Yang Z, Lou J, Carnell M, Vartoukian H, Gaus K, Rossy J. 2018. A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation. Nat Commun Apr 23;9(1):1597. doi: 10.1038/s41467-018-04088-w.
Ma Y, Pandzic E, Nicovich PR, Yamamoto Y, Kwiatek J, Pageon SV, Benda A, Rossy J, Gaus K. 2017. An intermolecular FRET sensor detects the dynamics of T cell receptor clustering. Nat Commun Apr 28;8:15100. doi: 10.1038/ncomms15100.
Ma Y, Yamamoto Y, Nicovich PR, Goyette J, Rossy J, Gooding JJ, Gaus K. 2017. A FRET sensor enables quantitative measurements of membrane charges in live cells. Nat Biotechnol Apr;35(4):363-370. doi: 10.1038/nbt.3828. Epub 2017 Mar 13. Erratum in: Nat Biotechnol. 2017 May 9;35(5):481.
Lou J, Rossy J, Deng Q, Pageon SV, Gaus. 2016. New Insights into how trafficking regulates T Cell receptor signaling. Front Cell Dev Biol 4:77.
Pageon SV, Tabarin T, Yamamoto Y, Ma Y, Bridgeman JS, Cohnen A, Benzing C, Gao Y, Crowther MD, Tungatt K, Dolton G, Sewell AK, Price DA, Acuto O, Parton RG, Gooding JJ, Rossy J, Rossjohn J, Gaus K. 2016. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proc Natl Acad Sci U S A 113 :E5454-63.
Pollock AH, Tedla N, Hancock SE, Cornely R, Mitchell TW, Kockx M, Parton RG, Rossy J*, Gaus K*. 2016. Prolonged intake of dietary lipids alters membrane structure and T cell responses in LDLr-/- mice. J Immunol 96(10):3993-4002. *Corresponding author
Kapoor-Kaushik N, Hinde E, Compeer EB, Yamamoto Y, Kraus F, Yang Z, Lou J, Pageon SV, Tabarin T, Gaus K, Rossy J. 2016. Distinct mechanisms regulate Lck spatial organization in activated T cells. Front Immunol 7:83.
Cornely R, Pollock AH, Rentero C, Norris SE, Alvarez-Guaita A, Grewal T, Mitchell T, Enrich C, Moss SE, Parton RG, Rossy J*, Gaus K*. 2016. Annexin A6 regulates interleukin-2-mediated T cell proliferation. Immunol Cell Biol Feb 8. doi: 10.1038/icb *Corresponding author.
Pham S, Tabarin T, Garvey M, Pade C, Rossy J, Monaghan P, Hyatt A, Böcking T, Leis A, Gaus K, Mak J. 2015. Cryo-electron microscopy and single molecule fluorescent microscopy detect CD4 receptor induced HIV size expansion prior to cell entry. Virology 486:121-133.
Pandžić E, Rossy J, Gaus K. 2015. Tracking molecular dynamics without tracking: image correlation of photo-activation microscopy. Methods Appl Fluoresc 3:014006.
Cochran BJ, Bisoendial RJ, Hou L, Glaros EN, Rossy J, Thomas SR, Barter PJ, Rye KA. 2014. Apolipoprotein A-I Increases Insulin Secretion and Production From Pancreatic β-Cells via a G-Protein-cAMP-PKA-FoxO1-Dependent Mechanism. Arterioscler Thromb Vasc Biol 34:2261-2267.
Rossy J*, Ma Y and Gaus K*. 2014. The organisation of the cell membrane: do proteins rule lipids? Curr Opin Chem Biol 20:54-59.*Corresponding author
Rossy J, Cohen E, Gaus K, Owen DM. 2014. Method for co-cluster analysis in multichannel single-molecule localisation data. Histochem Cell Biol 41:605-612.
Choi YI, Duke-Cohan JS, Chen W, Liu B, Rossy J, Tabarin T, Ju L, Gui J, Gaus K, Zhu C, Reinherz EL. 2014. Dynamic control of β1 integrin adhesion by the plexinD1-sema3E axis. Proc Natl Acad Sci U S A 111:379-384.
Owen DM, Williamson DJ, Boelen L, Magenau A, Rossy J, Gaus K. 2013. Quantitative analysis of three-dimensional fluorescence localization microscopy data. Biophys J 16;105:L05-7.
Benzing C, Rossy J, Gaus K. 2013. Do signalling endosomes play a role in T cell activation? FEBS J 280:5164-5176.
Rossy J, Pageon SV, Davis DM,Gaus K. 2013. Super-resolution microscopy of the immunological synapse. Curr Opin Immunol 25:307-12.
Rossy J, Owen DM, Williamson DJ, Yang Z, Gaus K. 2013. Conformational states of Lck regulate clustering in early T cell signalling. Nat Immunol 14:82-89.
Rossy J, Williamson DJ, Benzing C and Gaus K. 2012. The integration of signalling and the spatial organization of the T cell synapse. Front Immunol 3:352.
Rossy J, Williamson DJ, Gaus K. 2012. How does the kinase Lck phosphorylate the T cell receptor? Spatial organization as a regulatory mechanism. Front Immunol 3:167.
Pereira CF#, Rossy J#, Owen DM, Mak J, Gaus K. 2012. HIV taken by STORM: Super-resolution fluorescence microscopy of a viral infection. Virol J 9:84.# Equal first authors
Affentranger S, Martinelli S, Hahn J, Rossy J, Niggli V. 2011. Dynamic reorganization of flotillins in chemokine-stimulated human T-lymphocytes. BMC Cell Biol 22;12:28.
Williamson DJ#, Owen DM#, Rossy J#, Magenau A, Wehrmann M, Gooding JJ, Gaus K. 2011. Pre-existing clusters of the adaptor Lat do not participate in early T cell signaling events. Nat Immunol 12:655–666.# Equal first authors
Owen D, Rentero C, Rossy J, Magenau A, Williamson D, Rodriguez M, Gaus K. 2010. PALM microscopy and cluster analysis of protein heterogeneity at the cell surface. J Biophotonics 3:446-454.
Rossy J, Schlicht D, Engelhardt B and Niggli V. 2009. Flotillins interact with PSGL-1 in neutrophils and, upon stimulation, rapidly organize into membrane domains subsequently accumulating in the uropod. PLoS One 4: e5403.
Niggli V, Rossy J. 2008. Ezrin/radixin/moesin: versatile controllers of signaling molecules and of the cortical cytoskeleton. Int J Biochem Cell Biol 40:344-349.
Rossy J, Gutjahr MC, Blaser N, Schlicht D, Niggli V. 2007. Ezrin/moesin in motile Walker 256 carcinosarcoma cells: signal-dependent relocalization and role in migration. Exp Cell Res 313:1106-1120.
Gutjahr MC, Rossy J, Niggli V. 2005. Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells. Exp Cell Res 15; 308:422-38.