Biotechnology Institute Thurgau at the University of Konstanz
Third-party funding projects
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| Projektleiter | Projekttitel | Finanzierungsquelle | Laufzeit |
| Daniel Legler | Common and ligand-biased CCR7 signaling dynamics in guiding leukocyte migration | Schweiz. Nationalfonds SNF 310030_220205 | 2023-2027 |
| Daniel Legler | Masterstipendium und Gerätezuschuss | Crescere Stiftung Thurgau | 2022 |
| Daniel Legler | Doktorandenpatenschaften | Schuler-Nufer Stiftung | 2020-2024 |
| Jérémie Rossy | Understanding the dendritic cell side of the immunological synapse | Schweiz. Nationalfonds Projekt No. 201059 | 2021-2025 |
| Daniel Legler | Doktorandenstipendium | Crescere Stiftung Thurgau | 2020 |
| Daniel Legler | Spitzenforschung am BITg | TKB Jubiläums-Stiftung | 2019-2022 |
| Marcus Groettrup | Immunotherapy of breast carcinoma through combination of PLGA-microsphere based vaccination with immune checkpoint blockade | San Salvatore Foundation | 2020-2021 |
| Daniel Legler | Understanding ligand-biased, spatio-temporal CCR7 signaling in guiding leukocyte migration | Schweiz. Nationalfonds SNF 310030-189144 | 2019-2023 |
| Jérémie Rossy | Membrane scaffolding by Sorting Nexin 9 regulate CD28 signalling during T cell activation | Novartis Foundation for Medical-Biological Research | 2019 |
| Daniel Legler | Unravelling functional consequences of somatic human chemokine receptor CCR7 mutations in cancer | Novartis Foundation for Medical-Biological Research (Project No. 19B094) | 2019 |
| Daniel Legler, Annette Aichem | LI-COR Odyssey® Imaging System | Lotteriefonds des Kantons Thurgau | 2019 |
| Daniel Legler | Ko-Finanzierung eines TIRF-Mikroskops für die biomedizinische Forschung am BITg | Thurgauische Krebsliga | 2018 |
| Jérémie Rossy | Understanding the role of endosomes in T cells | Schweiz. Nationalfonds 31003A_172969 | 2017-2020 |
| Daniel Legler | Elucidating distinct spatio-temporal CCR7 signaling complexes in controlling immune cell migration | Schweiz. Nationalfonds SNF 31003A_169936 | 2016-2019 |
| Michael Basler | Identification of Immunoproteasome dependent factors involved in cytokine release and T cell differentiation | SwissLife Jubiläumsstiftung | 2016 |
| Marcus Groettrup | Investigating immunoproteasome inhibition as a new approach to colorectal cancer therapy | Krebsliga Schweiz | 2016-2019 |
| Daniel Legler | Ein purinerges Signalübertragungsrelais zur effizienten Zellmigration von Dendritischen Zellen und einer verbesserten Immunantwort gegen Infektionen und Krebs | Vontobel Stiftung | 2016-2018 |
| Marcus Groettrup, Annette Aichem | The role of FAT10 in the development of Leber congenital amaurosis (LCA) causing early childhood blindness: Characterizing the regulation and functional consequences of FAT10ylating phosphodiesterase 6 (PDE6) in the retina | Velux Stiftung | 2016-2019 |
| Daniel Legler, Marcus Thelen, Cornelia Halin, Antal Rot | Interplay of classical and atypical chemokine receptors in immune cell trafficking and dynamic microarchitecture of the secondary lymphoid organs | Schweiz. Nationalfonds Sinergia (CRSII3_160719) | 2015-2019 |
| Michael Basler | Identifikation der vom Immunproteasom abhängigen Faktoren, die eine Rolle in der Zytokinproduktion und T-Zelldifferenzierung spielen | SwissLife Jubiläumsstiftung | 2015 |
| Hesso Farhan | Systematic analysis of the regulation of the Golgi apparatus and its role in cell migration and polarity | Schweiz. Nationalfonds SNF 31003A_156913 | 2014-2017 |
| Daniel Legler | Brustkrebsmetastasierung | Thurgauische Krebsliga | 2013-2015 |
| Daniel Legler | Functional consequences of a second, intracellular GPCR signaling complex | Novartis Stiftung für Medizinisch-Biologische Forschung (Projekt Nr. 13B078) | 2013-2015 |
| Annette Aichem | Post-translational modification of the transcription factor JunB by the ubiquitin-like modifier FAT10 and its impact on CD4+ Th1/Th2 helper cell differentiation during inflammatory infections | Novartis Stiftung für Medizinisch-Biologische Forschung | 2013-2014 |
| Marcus Groettrup, Annette Aichem | The ubiquitin-like modifier FAT10 and its role in the pathogenesis of Leber congenital amaurosis causing early childhood blindness | Velux Stiftung | 2013-2015 |
| Daniel Legler | Differential signaling through the chemokine receptor CCR7 by two ligands | Schweiz. Nationalfonds SNF 31003A_143841 | 2012-2015 |
| Daniel Legler | High-throughput screening technology to identify biologics, ligands and ligand-induced interaction partners of G protein-coupled receptors | KTI CTI 12516.1 PFLS-LS | 2011-2012 |
| Marcus Groettrup | Immunoproteasome structure, assembly and function in the inflamed brain | Schweiz. Nationalfonds SNF 31003A_138451 | 2011-2014 |
| Hesso Farhan | Phosphorylation of Sec16 and the regulation of endoplasmic reticulum exit sites (ERES) | Schweiz. Nationalfonds SNF 31003A_135605 | 2011-2014 |
| Daniel Legler, Hesso Farhan, Marcus Groettrup | REquip: Laser scanning confocal microscope for imaging immunological and cell biological processes | Schweiz. Nationalfonds SNF 316030_133812 | 2011-2012 |
| Marcus Groettrup, Michael Basler | Inhibitors of the immunoproteasome for the treatment of multiple sclerosis in pre-clinical models | Schweiz. Multiple Sklerose Gesellschaft | 2011-2012 |
| Daniel Legler | Regulation of metastasis formation and cell migration by MALT1 | Pablo Frolich Stiftung | 2010-2011 |
| Daniel Legler | Beitrag zur Anschaffung eines neuen Zellsorters | Thurgauische Krebsliga | 2010 |
| Daniel Legler | Modulation of dendritic cell functions and migration by prostaglandin E2 | Schweiz. Nationalfonds SNF 31003A_127474 | 2009-2012 |
| Daniel Legler | Development of a high-throughput screening technology to identify ligands and ligand-induced interaction partners of G protein-coupled receptors | KTI CTI 9807.1 PFLS-LS | 2009-2011 |
| Marcus Groettrup | The failure of ER targeting as a source of antigen for presentation on MHC class I | Schweiz. Nationalfonds SNF 3100_063387 | 2008-2011 |
| Daniel Legler | Zwei Sterilarbeitsplätze zur Aufarbeitung von Tumorgeweben und Zellen | Thurgauische Krebsliga | 2006 |
| Daniel Legler | Regulation of sprouty-2, spred and RGS9 by prostaglandin E2: role in dendritic cell migration | Schweiz. Nationalfonds SNF 310030_112421 | 2006-2009 |
| Daniel Legler | Chemotaxis of human dendritic cells: regulation of chemokine receptor signal transduction through prostaglandin E2 | Prof. Dr. Cloëtta Stiftung | 2005-2010 |
| Daniel Legler | The role of prostaglandin E2 in dendritic cell-T cell interactions: towards the development of dendritic cell-based tumor vaccinations | Vontobel Stiftung | 2005-2008 |
| Marcus Groettrup, Daniel Legler | Regulation of CCR7 signal transduction through prostaglandin E2 and its role for dendritic cell migration and tumor vaccination | Krebsliga Schweiz OCS-01309-02-2003 | 2003-2005 |
